Endocrine Abstracts

Introduction: The risk of aortic dissection (AoD) is significantly increased (40 per 100,000/y) in women with Turner Syndrome (TS), but the clinical profile and management for those at risk are not well-established. To gain a better understanding, we present the experience of a single centre with multidisciplinary care, including dedicated cardiology, for management of TS in adulthood.Methods: Retrospective case-review of women develop...

Introduction: The risk of aortic dissection (AoD) is significantly increased (40 per 100,000/y) in women with Turner Syndrome (TS), but the clinical profile and management for those at risk are not well-established. To gain a better understanding, we present the experience of a single centre with multidisciplinary care, including dedicated cardiology, for management of TS in adulthood.Methods: Retrospective case-review of women develop...

Turner syndrome is a common chromosomal disorder affecting 1 in 2500 life female births. Turner syndrome is associated with congenital cardiovascular malformations of the aortic arch, systemic and pulmonary venous return with reported incidences ranging from 23 to 45%. These vascular malformations cause significant morbidity and mortality with increased incidence of aortic pathology, right heart strain and pulmonary hypertension as a result. In this investigation we retrospect...

Introduction: Elongated transverse aortic arch (ETA) has recently been described as the commonest abnormality (≅50%) in Turner syndrome (TS), exceeding the prevalence of bicuspid aortic valve (BAV; 10–30%) and aortic coarctation (CoA; 7–18%). Nevertheless only few studies focused on ETA. ETA was associated with BAV, CoA, 45,X and aortic dilatation.Aim: To evaluate the prevalence and associations of ETA in adult TS, unselected for cardiova...

Introduction: Women with turner syndrome (TS) have an increased risk of aortic dissection at young age. Bicuspid aortic valve (BAV) and aortic dilatation, both associated with TS, are risk factors. Preliminary studies suggested that cardiac MR (CMR) perfoms better than transthoracic echocardiography (TTE) for evaluating BAV and aortic dilatation, probably related to the frequent chest abnormalities in TS.Aim: To evaluate the ability and comparability of ...